asenapine maleate

Term ID

CHEBI:71245

Synonyms

• (+-)-asenapine maleate
• (3aRS,12bRS)-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo(2,3:6,7)oxepino(4,5-c)pyrrole (2Z)-2-butenedioate
• (3aRS,12bRS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-2-ium (2Z)-3-prop-2-enoate
• (3aRS,12bRS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-but-2-enedioate
• rac-(3aR,12bR)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-2-ium (2Z)-3-prop-2-enoate
• rac-(3aR,12bR)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-but-2-enedioate
• Saphris
• trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate

Definition

A racemate consisting of equal amounts of (R,R)- and (S,S)-asenapine maleate. Used for the acute treatment of schizophrenia and acute treatment of manic or mixed episodes associated with bipolar I disorder with or without psychotic features.

References

• CAS:85650-56-2
• KEGG:D02995
• PMCID:PMC3368685
• PMID:17440629
• PMID:17609744
• PMID:19088949
• PMID:19229381
• PMID:19876039
• PMID:20135021
• PMID:20216523
• PMID:20232719
• PMID:20448862
• PMID:20950326
• PMID:21274390
• PMID:21323396
• PMID:21446639
• PMID:21651314
• PMID:22778826
• Patent:EP1917267
• Patent:KR20080005253
• Patent:NZ562124
• Patent:WO2011159903
• Patent:ZA200708493
• Reaxys:3647286
• Wikipedia:Asenapine

Ontology

ChEBI  ( EBI )