Search Ontology:
ChEBI
dabigatran etexilate
- Term ID
- CHEBI:70746
- Synonyms
-
- dabigatran etexilate
- ethyl N-[(2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alaninate
- Definition
- An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl N-pyridin-2-yl-beta-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism.
- References
-
- CAS:211915-06-9
- Drug_Central:776
- HMDB:HMDB0015641
- KEGG:D07144
- PMID:21265583
- PMID:21429525
- PMID:21542663
- PMID:21748501
- PMID:21859976
- PMID:21881389
- PMID:22252796
- PMID:22276081
- PMID:22298812
- PMID:22318514
- PMID:22348256
- PMID:22422743
- PMID:22431533
- PMID:22488474
- PMID:22536678
- PMID:22552763
- PMID:22563715
- PMID:22564134
- PMID:22669799
- PMID:22782539
- PMID:22803489
- PMID:22995531
- PMID:23476049
- Patent:US2011275824
- Patent:WO2007047608
- Patent:WO2011061080
- Patent:WO2012027543
- Patent:WO2012077136
- Reaxys:15496119
- Ontology
- ChEBI ( EBI )
- is a type of
- has_functional_parent
-
- has_role
-
- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
-
Phenotype
Phenotype resulting from dabigatran etexilate
Phenotype where environments contain dabigatran etexilate
Phenotype modified by environments containing dabigatran etexilate
Human Disease / Model Data