Search Ontology:
ChEBI
alpha-methyl-L-tyrosine
- Term ID
- CHEBI:6912
- Synonyms
-
- (-)-alpha-Methyl-L-tyrosine
- (S)-alpha-Methyltyrosine
- alpha-methyl-L-p-tyrosine
- alpha-methyl-L-tyrosine
- alpha-methyl-p-tyrosine
- alpha-methyl-para-tyrosine
- alpha-Methyltyrosine
- L-alpha-Methyltyrosine
- Methyltyrosine
- metirosina
- metirosine
- metirosinum
- Metyrosine
- Definition
- An L-tyrosine derivative that consists of L-tyrosine bearing an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma.
- References
-
- CAS:672-87-7
- DrugBank:DB00765
- Drug_Central:1792
- KEGG:C07921
- KEGG:D00762
- PMID:28716505
- PMID:29353821
- PMID:29438107
- PMID:29668781
- Patent:US2011104765
- Reaxys:2368400
- Wikipedia:Metirosine
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Phenotype
Phenotype resulting from alpha-methyl-L-tyrosine
Phenotype where environments contain alpha-methyl-L-tyrosine
Phenotype modified by environments containing alpha-methyl-L-tyrosine
Human Disease Model