regorafenib hydrate

Term ID

CHEBI:68646

Synonyms

4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide monohydrate
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide--water (1/1)
regorafenib monohydrate
Stivarga

Definition

A hydrate that is the monohydrate form of anhydrous regorafenib. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy.

References

KEGG:D10137
Patent:WO2008043446
Reaxys:18329444

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrate

hydrate Show first 5 Terms
has_part: regorafenib

regorafenib Show first 5 Terms
has_role: antineoplastic agent hepatotoxic agent tyrosine kinase inhibitor

antineoplastic agent hepatotoxic agent tyrosine kinase inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from regorafenib hydrate

Phenotype where environments contain regorafenib hydrate

Phenotype modified by environments containing regorafenib hydrate

Human Disease Model