rivaroxaban

Term ID

CHEBI:68579

Synonyms

• 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide
• BAY 59-7939
• BAY59-7939
• rivaroxaban
• Xarelto

Definition

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery.

References

• CAS:366789-02-8
• DrugBank:DB06228
• Drug_Central:4182
• KEGG:D07086
• LINCS:LSM-5499
• PDBeChem:RIV
• PMCID:PMC7292653
• PMID:22042412
• PMID:22173426
• PMID:22187012
• PMID:22242932
• PMID:22272729
• PMID:22372178
• PMID:22387577
• PMID:22422332
• PMID:22533680
• PMID:22534269
• PMID:22534775
• PMID:22542983
• PMID:22651881
• PMID:22664783
• PMID:22701330
• PMID:22740145
• PMID:22777255
• PMID:22800431
• PMID:22811404
• PMID:22871192
• PMID:22884545
• PMID:22932305
• PMID:22958812
• PMID:23006523
• PMID:23014816
• PMID:30653475
• PMID:31784708
• PMID:32002769
• PMID:32023227
• PMID:32223113
• PMID:32223511
• PMID:32252075
• PMID:32265542
• PMID:32279215
• PMID:32296145
• PMID:32382756
• PMID:32519800
• PMID:32548552
• PMID:32548556
• Patent:EP1685841
• Patent:US2005182055
• Patent:US2007026065
• Patent:US2009036504
• Patent:US2010151011
• Patent:US2011034453
• Patent:US2011112083
• Patent:US2011152266
• Patent:US2011288294
• Patent:US7816355
• Patent:WO2004060887
• Patent:WO2005068456
• Patent:WO2008140220
• Patent:WO2011080341
• Patent:WO2012035057
• Patent:WO2012051692
• Reaxys:10206739
• Wikipedia:Rivaroxaban

Ontology

ChEBI  ( EBI )