Search Ontology:
ChEBI

dolastatin 10

Term ID
CHEBI:67357
Synonyms
  • DLS-10
  • dolastatin-10
  • N,N-dimethyl-L-valyl-N-[(3R,4S,5S)-3-methoxy-1-{(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidin-1-yl}-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide
Definition
A tetrapeptide that is isolated from the sea hare Dolabella auricularia. It is a potent anticancer agent which inhibits tubulin polymerization.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from dolastatin 10
Phenotype where environments contain dolastatin 10
Phenotype modified by environments containing dolastatin 10
Human Disease Model
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