Search Ontology:
ChEBI
MK-2206
- Term ID
- CHEBI:67271
- Synonyms
-
- 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one
- 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one
- MK 2206
- MK-2206 free base
- MK2206
- Definition
- An organic heterotricyclic compound that is [1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one substituted by 4-(1-aminocyclobutyl)phenyl and phenyl groups at positions 8 and 9, respectively. It is an allosteric Akt inhibitor.
- References
-
- CAS:1032349-93-1
- DrugBank:DB16828
- LINCS:LSM-1057
- PMID:30033751
- PMID:30613632
- PMID:30943918
- PMID:31463691
- PMID:31714586
- PMID:31780937
- PMID:32116708
- PMID:32194695
- PMID:32738099
- PMID:33775646
- PMID:33803402
- PMID:34122406
- PMID:34322387
- PMID:34666331
- PMID:35434236
- PMID:35457111
- PMID:35765523
- PMID:35992874
- PMID:36331743
- PMID:36359901
- PMID:36441491
- PMID:36644819
- PMID:37222135
- PMID:37521473
- PMID:37947157
- PMID:38850717
- PMID:39182598
- Reaxys:18391321
- Wikipedia:MK-2206
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from MK-2206
Phenotype where environments contain MK-2206
Phenotype modified by environments containing MK-2206
Human Disease Model