laurolistine

Term ID

CHEBI:66557

Synonyms

(6aS)-1,10-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol
1,10-Dimethoxy-6a-alpha-noraporphine-2,9-diol
4H-Dibenzo(de,g)quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-
Dimethoxy-1,10 dihydroxy-2,9 nor-aporphine
Norboldine

Definition

An aporphine alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV-1 integrase.

References

CAS:5890-18-6
HMDB:HMDB0040974
KEGG:C16984
PMID:12237535
Reaxys:42729

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: aporphine alkaloid aromatic ether phenols

aporphine alkaloid aromatic ether phenols Show first 5 Terms
has_functional_parent: aporphine

aporphine Show first 5 Terms
has_role: HIV-1 integrase inhibitor metabolite

HIV-1 integrase inhibitor metabolite Show first 5 Terms
inverse has_functional_parent: (+)-N-(methoxycarbonyl)-N-norboldine

(+)-N-(methoxycarbonyl)-N-norboldine Show first 5 Terms

Phenotype

Phenotype resulting from laurolistine

Phenotype where environments contain laurolistine

Phenotype modified by environments containing laurolistine

Human Disease / Model Data