jaspamide

Term ID

CHEBI:66104

Synonyms

• (+)-Jasplakinolide
• (4R,7R,10S,13S,15E,17R,19S)-7-[(2-bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone
• beta-Alanine, N-(2-bromo-N-(N-(8-hydroxy-2,4,6-trimethyl-1-oxo-4-nonenyl)-L-alanyl)-N-methyl-D-tryptophyl)-L-3-(4-hydroxyphenyl)-, p-lactone, (2S-(2R*,4E,6S*,8R*))-
• Jaspamide
• Jasplakinolide

Definition

A cyclodepsipeptide isolated from Jaspis splendens and has been shown to exhibit antineoplastic activity. It is an actin polymerization and stabilization inducer.

References

• CAS:102396-24-7
• KEGG:C16883
• KNApSAcK:C00026975
• PMID:10339509
• PMID:11154977
• PMID:20678932
• PMID:21241058
• PMID:22115418
• PMID:23261645
• PMID:30736370
• PMID:3190203
• PMID:32084355
• PMID:33353294
• PMID:33515365
• PMID:34105487
• Patent:KR20030085421
• Reaxys:4649870

Ontology

ChEBI  ( EBI )

Resources

CTD