glomosporin

Term ID

CHEBI:65975

Synonyms

2-[(18R)-9,12-bis(2-amino-2-oxoethyl)-3-[(1R)-1-hydroxyethyl]-6,21-bis(hydroxymethyl)-25-(2-hydroxytetradecan-2-yl)-18-methyl-2,5,8,11,14,17,20,23-octaoxo-1-oxa-4,7,10,13,16,19,22-heptazacyclopentacos-15-yl]acetic acid
[(3R,18R)-9,12-bis(2-amino-2-oxoethyl)-3-[(1R)-1-hydroxyethyl]-6,21-bis(hydroxymethyl)-25-(2-hydroxytetradecan-2-yl)-18-methyl-2,5,8,11,14,17,20,23-octaoxo-1-oxa-4,7,10,13,16,19,22-heptaazacyclopentacosan-15-yl]acetic acid

Definition

A cyclodepsipeptide consisting of a 3,4-dihydroxy-4-methylhexadecanoyl group attached to the amino terminus of the linear heptapeptide Ser-D-Ala-Asp-Asn-Asn-Ser-D-allo-Thr which is cyclised head-to-tail via the 3-hydroxy group on the hexadecanoyl chain. It is an antifungal drug isolated from the barley solid culture of the fungus Glomospora sp.

References

PMID:10908117
PMID:10966075
Reaxys:8672918

Ontology

ChEBI ( EBI )

Relationships

is a type of: cyclodepsipeptide lactam monocarboxylic acid peptide antibiotic primary alcohol ... Show All 7 Terms

cyclodepsipeptide lactam monocarboxylic acid peptide antibiotic primary alcohol secondary alcohol tertiary alcohol Show first 5 Terms
has_functional_parent: 3,4-dihydroxy-4-methylhexadecanoic acid

3,4-dihydroxy-4-methylhexadecanoic acid Show first 5 Terms
has_role: antifungal agent fungal metabolite

antifungal agent fungal metabolite Show first 5 Terms

Phenotype

Phenotype resulting from glomosporin

Phenotype where environments contain glomosporin

Phenotype modified by environments containing glomosporin

Human Disease Model