Search Ontology:
ChEBI

BE-23372M

Term ID
CHEBI:65473
Synonyms
  • (3E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2(3H)-one
Definition
A butenolide that is furan-2(3H)-one substituted by a 3,4-dihydroxybenzylidene group at position 3 and a 3,4-dihydroxyphenyl group at position 5 (the 3E stereoisomer). It is isolated from the fermentation broth of the fungal strain Rhizoctonia solani F23372 and has been found to possess significant tyrosine kinase inhibitory potential. It also inhibits the growth of A431 human epidermoid carcinoma and MKN-7 human stomach cancer cell lines.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from BE-23372M
Phenotype where environments contain BE-23372M
Phenotype modified by environments containing BE-23372M
Human Disease Model
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