apratoxin D

Term ID

CHEBI:65421

Synonyms

• (3S,5S,7S,8S,12S,13E,17S,20S,23S,28aS)-23-[(2S)-butan-2-yl]-3-[(2S)-4,4-dimethylpentan-2-yl]-7-hydroxy-17-(4-methoxybenzyl)-5,8,14,19,20,22-hexamethyl-3,4,5,6,7,8,11,12,16,17,19,20,22,23,26,27,28,28a-octadecahydro-1H-12,9-(azeno)pyrrolo[2,1-c][1,19,4,7,10

Definition

An aprotoxin having the common aprotoxin cyclodepsipeptide skeleton where the isoleucyl residue carries an N-methyl substituent and the side-chain adjacent to the lactone is (2R)-4,4-dimethylpentan-2-yl. It is isolateed from Lyngbya majuscula and Lyngbya sordida and exhibits anticancer properties.

References

• PMID:18444683
• PMID:23057680
• Reaxys:18840921

Ontology

ChEBI  ( EBI )