Search Ontology:
ChEBI
clobenpropit
- Term ID
- CHEBI:64177
- Synonyms
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- 3-(1H-imidazol-4-yl)propyl N-(4-chlorobenzyl)carbamimidothioate
- S-(3-(4(5)-Imidazolyl))propyl-N-(4-chlorobenzyl)isothiourea
- Definition
- An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM.
- References
-
- CAS:145231-45-4
- KEGG:C17934
- LINCS:LSM-3600
- PMID:19895842
- PMID:20014479
- PMID:20093321
- PMID:20197375
- PMID:20432621
- PMID:20511290
- PMID:21134907
- PMID:21272571
- PMID:21554104
- PMID:21793031
- PMID:22003888
- PMID:22005500
- PMID:22011436
- PMID:22115898
- PMID:22331799
- Reaxys:5822910
- Wikipedia:Clobenpropit
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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- inverse is_conjugate_acid_of
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- is_conjugate_base_of
-
Phenotype
Phenotype resulting from clobenpropit
Phenotype where environments contain clobenpropit
Phenotype modified by environments containing clobenpropit
Human Disease Model