(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride

Term ID

CHEBI:64115

Synonyms

(+)-AJ 76 hydrochloride
(1S,2R)-5-methoxy-1-methyl-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride
(1S,2R)-5-methoxy-1-methyl-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium chloride
cis-(+)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride

Definition

A hydrochloride obtained by reaction of (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin with one equivalent of hydrochloric acid. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively).

References

Reaxys:6076657

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrochloride

hydrochloride Show first 5 Terms
has_part: (1S,2R)-5-methoxy-1-methyl-2-(propylammonio)tetralin(1+)

(1S,2R)-5-methoxy-1-methyl-2-(propylammonio)tetralin(1+) Show first 5 Terms
has_role: dopaminergic antagonist

dopaminergic antagonist Show first 5 Terms

Phenotype

Phenotype resulting from (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride

Phenotype where environments contain (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride

Phenotype modified by environments containing (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride

Human Disease Model