Search Ontology:
ChEBI
SB 224289 hydrochloride
- Term ID
- CHEBI:64067
- Synonyms
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- (1'-methyl-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride
- 1'-methyl-5-{[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl}-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidinium] chloride
- Definition
- A hydrochloride that is the monohydrochloride salt of SB 224289. Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays >60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo.
- References
-
- PMID:20306273
- Reaxys:8248456
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_part
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- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from SB 224289 hydrochloride
Phenotype where environments contain SB 224289 hydrochloride
Phenotype modified by environments containing SB 224289 hydrochloride
Phenotype affecting SB 224289 hydrochloride
Human Disease Model