Search Ontology:
ChEBI
leflunomide
- Term ID
- CHEBI:6402
- Synonyms
-
- 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
- 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
- 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide
- alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide
- Arava
- leflunomida
- leflunomide
- leflunomidum
- Definition
- A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
- References
-
- Beilstein:4323174
- CAS:75706-12-6
- DrugBank:DB01097
- Drug_Central:1552
- HMDB:HMDB0015229
- KEGG:C07905
- KEGG:D00749
- LINCS:LSM-3771
- PMID:10515382
- PMID:10702725
- PMID:10890256
- PMID:11043056
- PMID:11053058
- PMID:11067959
- PMID:11271257
- PMID:11333342
- PMID:11340750
- PMID:11391470
- PMID:11475244
- PMID:11522581
- PMID:11707749
- PMID:11718154
- PMID:11876141
- PMID:11884931
- PMID:11994686
- PMID:12017890
- PMID:12074690
- PMID:12833393
- PMID:14622739
- PMID:15030575
- PMID:15127968
- PMID:15127974
- PMID:15188371
- PMID:15214907
- PMID:15385935
- PMID:15489872
- PMID:15537652
- PMID:15652966
- PMID:15665760
- PMID:15789891
- PMID:15899055
- PMID:15934905
- PMID:16106593
- PMID:16142756
- PMID:16202258
- PMID:16284916
- PMID:16638062
- PMID:16638420
- PMID:16645972
- PMID:16688677
- PMID:16769661
- PMID:16778342
- PMID:17366662
- PMID:17604599
- PMID:17646975
- PMID:17854740
- PMID:18034546
- PMID:18173611
- PMID:18413415
- PMID:18496682
- PMID:18663553
- PMID:18688040
- PMID:19169882
- PMID:19190124
- PMID:19344337
- PMID:19581389
- PMID:19715969
- PMID:19751817
- PMID:19770782
- PMID:7496341
- PMID:7676489
- PMID:8610393
- PMID:9075844
- PMID:9123314
- PMID:9625011
- PMID:9777697
- Patent:DE2854439
- Patent:US4284786
- Reaxys:4323174
- Wikipedia:Leflunomide
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_role
Phenotype
Phenotype resulting from leflunomide
Phenotype where environments contain leflunomide
Phenotype modified by environments containing leflunomide
Human Disease Model