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ChEBI

N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol

Term ID
CHEBI:63988
Synonyms
  • 1-phenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
  • 3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
  • 3-Allyl-2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
  • N-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
  • SK&F 77434
  • SKF 77434
  • Skf-77434
Definition
A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, an allyl substituent at position 3 and two hydroxy substituents at positions 7 and 8. Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse is_conjugate_acid_of
is_conjugate_base_of
Phenotype
Phenotype resulting from N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol
Phenotype where environments contain N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol
Phenotype modified by environments containing N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol
Human Disease Model