Search Ontology:
ChEBI
pemetrexed
- Term ID
- CHEBI:63616
- Synonyms
-
- N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid
- pemetrexed
- Definition
- An N-acylglutamic acid in which the N-acyl group is specified as 4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT).
- References
-
- CAS:137281-23-3
- DrugBank:DB00642
- KEGG:D07472
- LINCS:LSM-6353
- PMID:21129871
- PMID:21831719
- PMID:21900836
- PMID:21937141
- PMID:22021325
- PMID:22116317
- PMID:22124474
- PMID:22134068
- PMID:22201521
- PMID:22223137
- PMID:22237209
- PMID:22240216
- PMID:22243773
- PMID:22244076
- PMID:22258853
- Patent:EP432677
- Patent:US5344932
- Reaxys:9097855
- Wikipedia:Pemetrexed
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_base_of
-
- is_conjugate_acid_of
-
Phenotype
Phenotype resulting from pemetrexed
Phenotype where environments contain pemetrexed
Phenotype modified by environments containing pemetrexed
Human Disease Model