Search Ontology:
ChEBI
BGJ-398
- Term ID
- CHEBI:63451
- Synonyms
-
- 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea
- BGJ398
- NVP-BGJ398
- Definition
- A member of the class of phenylureas that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 2,6-dichloro-3,5-dimethoxyphenyl group, while the hydrogens attached to the other nitrogen are replaced by a methyl group and a 6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl group. It is a potent and selective fibroblast growth factor receptor inhibitor.
- References
-
- LINCS:LSM-1184
- PMID:21936542
- Reaxys:12512466
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from BGJ-398
Phenotype where environments contain BGJ-398
Phenotype modified by environments containing BGJ-398
Human Disease Model