felypressin

Term ID

CHEBI:60564

Synonyms

• 1-{[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13,16-dibenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-lysylglycinamide
• 2-(L-phenylalanine)-8-L-lysinevasopressin
• felipresina
• felypressin
• felypressine
• felypressinum
• L-cysteinyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1-6)disulfide
• Phe(2)-Lys(8)-vasopressin
• PLV-2

Definition

A synthetic nonapeptide comprising cysteinyl, phenylalanyl, phenylalanyl, glutaminyl, asparaginyl, cysteinyl, prolyl, lysyl, and glycinamide residues in sequence, with a disulfide bridge joining the two cysteine residues. Its antidiuretic effects are less than those of vasopressin. It is used as a vasoconstrictor in local anaesthetic injections for dental use, and is an ingredient of preparations that have been used for treatment of pain and inflammation of the mouth.

References

• CAS:56-59-7
• DrugBank:DB00093
• Drug_Central:4910
• KEGG:D04137
• Patent:GB928607
• Patent:US3232923
• Reaxys:13260124

Ontology

ChEBI  ( EBI )

Resources

CTD