Search Ontology:
ChEBI
amorolfine
- Term ID
- CHEBI:599440
- Synonyms
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- (+-)-cis-2,6-dimethyl-4-(2-methyl-3-(p-tert-pentylphenyl)propyl)morpholine
- (2R,6S)-2,6-dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine
- amorolfina
- amorolfine
- amorolfinum
- meso-2,6-dimethyl-4-(2-methyl-3-(p-tert-pentylphenyl)propyl)morpholine
- meso-2,6-dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine
- Definition
- A member of the class of morpholines that is cis-2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a racemic 2-methyl-3-[p-(2-methylbutan-2-yl)phenyl]propyl group. An inhibitor of the action of squalene monooxygenase, Delta(14) reductase and D7-D8 isomerase and an antifungal agent, it is used (generally as its hydrochloride salt) for the topical treatment of fungal nail and skin infections.
- References
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- Beilstein:8154195
- CAS:78613-35-1
- Drug_Central:188
- KEGG:D01720
- KEGG:D02923
- PMID:17620378
- Wikipedia:Amorolfine
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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- inverse is_conjugate_base_of
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- is_conjugate_acid_of
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Show first 5 Terms
Phenotype
Phenotype resulting from amorolfine
Phenotype where environments contain amorolfine
Phenotype modified by environments containing amorolfine
Human Disease Model