Search Ontology:
ChEBI
granisetron
- Term ID
- CHEBI:5537
- Synonyms
-
- 1-methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide
- 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
- APF 530
- APF530
- BRL 43694
- granisetron
- granisetronum
- Kevatril
- Sancuso
- Sustol
- Definition
- A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 1-methyl-1H-indazole-3-carboxylic acid with the primary amino group of (3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine. A selective 5-HT3 receptor antagonist, it is used (generally as the monohydrochloride salt) to manage nausea and vomiting caused by cancer chemotherapy and radiotherapy, and to prevent and treat postoperative nausea and vomiting.
- References
-
- CAS:109889-09-0
- DrugBank:DB00889
- Drug_Central:1329
- HMDB:HMDB0015026
- KEGG:C07023
- KEGG:D04370
- PDBeChem:CWB
- PMID:1650335
- PMID:2169778
- PMID:22452942
- PMID:24388937
- PMID:2540014
- PMID:25834466
- PMID:25866983
- PMID:26289588
- PMID:26812081
- PMID:26925101
- PMID:26997579
- PMID:27073822
- PMID:27129842
- PMID:27162748
- PMID:27184113
- PMID:27186139
- PMID:27358385
- PMID:27382819
- PMID:27400689
- PMID:27571447
- PMID:27650869
- PMID:27703112
- PMID:27746523
- PMID:27809336
- PMID:27895421
- PMID:27915445
- PMID:28002447
- PMID:28061543
- PMID:28168082
- PMID:28211304
- Patent:EP200444
- Patent:US4886808
- Reaxys:3655275
- Wikipedia:Granisetron
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from granisetron
Phenotype where environments contain granisetron
Phenotype modified by environments containing granisetron
Human Disease Model