donepezil hydrochloride

Term ID

CHEBI:4696

Synonyms

(+-)-2-((1-Benzyl-4-piperidyl)methyl)-5,6-dimethoxy-1-indanone hydrochloride
1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl
Donepezil HCl
rac-1-benzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]piperidinium chloride
rac-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one hydrochloride

Definition

A racemate comprising equimolar amounts of (R)- and (S)- donepezil hydrochloride. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.

References

Beilstein:7062905
CAS:120011-70-3
DrugBank:DB00843
KEGG:D00670

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: racemate

racemate Show first 5 Terms
has_part: (R)-donepezil hydrochloride (S)-donepezil hydrochloride

(R)-donepezil hydrochloride (S)-donepezil hydrochloride Show first 5 Terms
has_role: EC 3.1.1.7 (acetylcholinesterase) inhibitor

EC 3.1.1.7 (acetylcholinesterase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from donepezil hydrochloride

Phenotype where environments contain donepezil hydrochloride

Phenotype modified by environments containing donepezil hydrochloride

Human Disease Model