hydroxyurea

Term ID

CHEBI:44423

Synonyms

• carbamohydroxamic acid
• carbamohydroximic acid
• carbamoyl oxime
• carbamyl hydroxamate
• hidroxicarbamida
• hydrea
• Hydroxycarbamid
• Hydroxycarbamide
• hydroxycarbamidum
• Hydroxyharnstoff
• Hydroxyurea
• N-carbamoylhydroxylamine
• N-hydroxyurea
• oxyurea

Definition

A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.

References

• Beilstein:1741548
• CAS:127-07-1
• DrugBank:DB01005
• Drug_Central:1399
• Gmelin:130423
• HMDB:HMDB0015140
• KEGG:C07044
• KEGG:D00341
• MetaCyc:HYDROXY-UREA
• PDBeChem:NHY
• PMID:11285159
• PMID:11298103
• PMID:11364534
• PMID:11365149
• PMID:11391710
• PMID:12107454
• PMID:14988684
• PMID:15772364
• PMID:15994344
• PMID:16356682
• PMID:22983419
• PMID:23318979
• PMID:23643402
• PMID:23696560
• PMID:9271088
• Patent:US2705727
• Reaxys:1741548
• Wikipedia:Hydroxyurea

Ontology

ChEBI  ( EBI )

Resources

CTD