Search Ontology:
ChEBI

demecarium bromide

Term ID
CHEBI:4391
Synonyms
  • (m-hydroxyphenyl)trimethylammonium bromide decamethylenebis(methylcarbamate)
  • 3,3'-{decane-1,10-diylbis[(methylcarbamoyl)oxy]}bis(N,N,N-trimethylanilinium) dibromide
  • bromure de demecarium
  • bromuro de demecario
  • decamethylenebis(m-dimethylaminophenyl-N-methylcarbamate)dimethobromide
  • decamethylenebis(N-methylcarbamic acid m-dimethylaminophenyl ester) bromomethylate
  • demecarii bromidum
  • demecarium bromide
  • N,N'-bis(3-trimethylammoniumphenoxycarbonyl)-N,N'-dimethyldecamethylenediamine dibromide
Definition
The methobromide salt of the N,N'-bis[3-(dimethylamino)phenyl carbamate] derivative of 2,13-diazatetradecane. It is an inhibitor of acetylcholinesterase and pseudocholinesterase, with a long duration of action. It is used in the treatment of chronic open-angle glaucoma: in the eye, it causes constriction of the iris sphincter muscle and the ciliary muscle, facilitating the outflow of the aqueous humor and so reducing intraocular pressure.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from demecarium bromide
Phenotype where environments contain demecarium bromide
Phenotype modified by environments containing demecarium bromide
Human Disease Model