L-propargylglycine

Term ID

CHEBI:43797

Synonyms

(2S)-2-aminopent-4-ynoic acid
(S)-2-amino-4-pentynoic acid
(S)-2-propargylglycine
(S)-alpha-propargylglycine
(S)-propargylglycine
L-2-propynylglycine
L-C-propargylglycine
L-PROPARGYLGLYCINE

Definition

A non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens has been replaced by an ethynyl group. It causes the irreversible inactivation of gamma-cystathionase (also known as cystathionine gamma-lyase) and is used as an affinity labeling reagent for gamma-cystathionase and other enzymes.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: non-proteinogenic L-alpha-amino acid terminal acetylenic compound

non-proteinogenic L-alpha-amino acid terminal acetylenic compound Show first 5 Terms
has_role: EC 1.4.3.2 (L-amino-acid oxidase) inhibitor EC 2.5.1.48 (cystathionine gamma-synthase) inhibitor EC 2.6.1.2 (alanine transaminase) inhibitor

EC 1.4.3.2 (L-amino-acid oxidase) inhibitor EC 2.5.1.48 (cystathionine gamma-synthase) inhibitor EC 2.6.1.2 (alanine transaminase) inhibitor Show first 5 Terms
inverse has_functional_parent: L-beta-ethynylserine

L-beta-ethynylserine Show first 5 Terms
inverse is_tautomer_of: L-propargylglycine zwitterion

L-propargylglycine zwitterion Show first 5 Terms
is_tautomer_of: L-propargylglycine zwitterion

L-propargylglycine zwitterion Show first 5 Terms

Phenotype

Phenotype resulting from L-propargylglycine

Phenotype where environments contain L-propargylglycine

Phenotype modified by environments containing L-propargylglycine

Human Disease Model