Search Ontology:
ChEBI
cosyntropin
- Term ID
- CHEBI:3901
- Synonyms
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- adrenocorticotropic hormone 1-24
- alpha(1-24)-corticotrophin
- ATCH (1-24)
- beta(1-24)-corticotrophin
- corticotropin-(1-24)
- corticotropin-(1-24) tetracosapeptide
- Cosyntropin
- L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyline
- SerTyrSerMetGluHisPheArgTrpGlyLysProValGlyLysLysArgArgProValLysValTyrPro
- SYSMEHFRWGKPVGKKRRPVKVYP
- tetracosactide
- Definition
- A synthetic peptide that is identical to the 24-amino acid segment at the N-terminal of adrenocorticotropic hormone (corticotropin). A segment similar in all species, it contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. It is used diagnostically to investigate adrenocortical insufficiency.
- References
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- CAS:16960-16-0
- DrugBank:DB01284
- Drug_Central:4516
- KEGG:D00284
- PMCID:PMC10554854
- PMCID:PMC8089304
- PMCID:PMC8090221
- PMCID:PMC8265910
- PMCID:PMC9625163
- PMID:31789828
- PMID:33978314
- PMID:35035309
- PMID:35044272
- PMID:35487459
- PMID:36060940
- PMID:37625985
- PMID:37651920
- PMID:37816309
- PMID:38222249
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_role
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Phenotype
Phenotype resulting from cosyntropin
Phenotype where environments contain cosyntropin
Phenotype modified by environments containing cosyntropin
Human Disease Model