2-methylbutyric acid

Term ID

CHEBI:37070

Synonyms

2-methybutyric acid
2-methylbutanoic acid
2-Methylbutyric acid
alpha-methyl butyric acid
alpha-methylbutyric acid
butane-2-carboxylic acid
ethylmethylacetic acid
methylethylacetic acid

Definition

A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria.

References

CAS:116-53-0
DrugBank:DB03741
HMDB:HMDB0002176
KEGG:C18319
LIPID_MAPS_instance:LMFA01020072
PMID:15615815
PMID:16751541
PMID:18828792
PMID:22202876
PMID:3372640
Reaxys:1098537

Ontology

ChEBI ( EBI )

Relationships

is a type of: methylbutyric acid

methylbutyric acid Show first 5 Terms
has subtype: (R)-2-methylbutyric acid (S)-2-methylbutyric acid

(R)-2-methylbutyric acid (S)-2-methylbutyric acid Show first 5 Terms
has_role: bacterial metabolite human metabolite

bacterial metabolite human metabolite Show first 5 Terms
inverse has_functional_parent: 1S,6R-di(2-)methylbutanoyloxy-4S-hydroxy-8S-benzoyloxy-9R-(3-)furancarbonyloxy-13-acetyloxy-beta-dihydroagarofuran 2-hydroxy-2-methylbutyric acid 2-methylbutanoyl-CoA 2-methylbutyrylcarnitine ethyl 2-methylbutyrate ... Show All 7 Terms

1S,6R-di(2-)methylbutanoyloxy-4S-hydroxy-8S-benzoyloxy-9R-(3-)furancarbonyloxy-13-acetyloxy-beta-dihydroagarofuran 2-hydroxy-2-methylbutyric acid 2-methylbutanoyl-CoA 2-methylbutyrylcarnitine ethyl 2-methylbutyrate N-(2-methylbutanoyl)glycine trichanolide Show first 5 Terms
inverse is_conjugate_base_of: 2-methylbutyrate

2-methylbutyrate Show first 5 Terms
is_conjugate_acid_of: 2-methylbutyrate

2-methylbutyrate Show first 5 Terms

Phenotype

Phenotype resulting from 2-methylbutyric acid

Phenotype where environments contain 2-methylbutyric acid

Phenotype modified by environments containing 2-methylbutyric acid

Human Disease Model