Search Ontology:
ChEBI
tolvaptan
- Term ID
- CHEBI:32246
- Synonyms
-
- (+-)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide
- (+-)-tolvaptan
- (RS)-tolvaptan
- Jinarc
- Jynarque
- N-(4-{[(5RS)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide
- OPC 41061
- OPC-41061
- rac-N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide
- RS-tolvaptan
- Samsca
- tolvaptan
- tolvaptanum
- Definition
- A racemate comprising of equimolar amounts of (R)- and (S)-tolvaptan. It is a selective vasopressin V2 receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency.
- References
-
- CAS:150683-30-0
- DrugBank:DB06212
- Drug_Central:4110
- KEGG:D01213
- PMID:12742979
- PMID:16211205
- PMID:33078835
- PMID:34070416
- PMID:34386666
- PMID:34476570
- PMID:34514204
- PMID:34526469
- PMID:34554640
- PMID:37214762
- PMID:37466863
- PMID:37516894
- PMID:37587049
- PMID:37845144
- PMID:37845430
- PMID:37916285
- PMID:37982946
- PMID:38097698
- PMID:38288467
- PMID:38337413
- PMID:38344178
- PMID:38396765
- PMID:38414126
- PMID:38423003
- PMID:38468548
- PMID:38494546
- PMID:38509003
- PMID:38512373
- PMID:38562967
- PMID:38577748
- PMID:38606040
- PMID:38608748
- PMID:38616432
- PMID:38652561
- PMID:38710808
- PMID:38717378
- Wikipedia:Tolvaptan
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_part
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- has_role
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- inverse has_functional_parent
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Show first 5 Terms
Phenotype
Phenotype resulting from tolvaptan
Phenotype where environments contain tolvaptan
Phenotype modified by environments containing tolvaptan
Human Disease Model