formoterol fumarate

Term ID

CHEBI:31633

Synonyms

formoterol hemifumarate
rac-bis[(2R)-N-{(2R)-2-[3-(formylamino)-4-hydroxyphenyl]-2-hydroxyethyl}-1-(4-methoxyphenyl)propan-2-aminium] (2E)-but-2-enedioate
rac-N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide (2E)-but-2-enedioate

Definition

A racemate consisting of equal amounts of arformoterol fumarate (the active enantiomer) and (S,S)-formoterol fumarate (the inactive enantiomer). It is used (particularly in its dihydrate form) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease (any progressive respiratory disease that makes it harder to breathe over time, such as chronic bronchitis and emphysema).

References

CAS:43229-80-7
DrugBank:DB00983
KEGG:D01373
PMID:18655841
PMID:20477569
Reaxys:8463050

Ontology

ChEBI ( EBI )

Relationships

is a type of: racemate

racemate Show first 5 Terms
has_part: (S,S)-formoterol fumarate arformoterol fumarate formoterol(1+)

(S,S)-formoterol fumarate arformoterol fumarate formoterol(1+) Show first 5 Terms
has_role: anti-asthmatic drug beta-adrenergic agonist bronchodilator agent

anti-asthmatic drug beta-adrenergic agonist bronchodilator agent Show first 5 Terms
inverse has_part: Bevespi Aerosphere

Bevespi Aerosphere Show first 5 Terms

Phenotype

Phenotype resulting from formoterol fumarate

Phenotype where environments contain formoterol fumarate

Phenotype modified by environments containing formoterol fumarate

Human Disease Model