ergometrine maleate

Term ID

CHEBI:31554

Synonyms

• 9,10-didehydro-N-((S)-2-hydroxy-1-methylethyl)-6-methylergoline-8beta-carboxamide maleate (1:1)
• ergometrin acid maleate
• ergometrine hydrogen maleate
• ergometrine maleate (1:1)
• ergonovine hydrogen maleate
• ergonovine maleate
• ergonovine, maleate (1:1)
• N-[(2S)-1-hydroxypropan-2-yl]-6-methyl-9,10-didehydroergoline-8beta-carboxamide (2Z)-but-2-enedioate

Definition

A maleate salt resulting form the reaction of equimolar amounts of maleic acid and ergometrine. It is used in the active management of the third stage of labour, and to prevent or treat postpartum of postabortal haemorrhage caused by uterine atony: by maintaining uterine contraction and tone, blood vessels in the uterine wall are compressed and blood flow reduced.

References

• CAS:129-51-1
• DrugBank:DB01253
• HMDB:HMDB0015383
• KEGG:D01163
• Reaxys:3855736

Ontology

ChEBI  ( EBI )