droxidopa

Term ID

CHEBI:31524

Synonyms

• (-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid
• (2S,3R)-3,4-dihydroxy-phenylserine
• (betaR)-beta,3-dihydroxy-L-tyrosine
• Dops
• droxidopa
• droxidopum
• Droxydopa
• L-Dihydroxyphenylserine
• L-DOPS
• L-threo-dihydroxyphenylserine
• L-Threodops
• Northera
• SM 5688
• threo-Dopaserine

Definition

A serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension

References

• CAS:23651-95-8
• DrugBank:DB06262
• Drug_Central:971
• HMDB:HMDB0015627
• KEGG:D01277
• PMID:11710796
• PMID:20063034
• PMID:20207766
• PMID:20220040
• PMID:21705113
• PMID:22561478
• PMID:22610782
• PMID:23224983
• PMID:24224390
• PMID:24326693
• PMID:24517276
• PMID:24644107
• PMID:24729712
• PMID:24883005
• PMID:24944260
• PMID:24958960
• Patent:JP2005247828
• Patent:NZ579368
• Patent:US2008221170
• Patent:US2012010293
• Patent:US2013253061
• Reaxys:7112431
• Wikipedia:Droxidopa

Ontology

ChEBI  ( EBI )

Resources

CTD