Search Ontology:
ChEBI

crotamiton

Term ID
CHEBI:31439
Synonyms
  • crotalgin
  • crotamiton
  • crotamitone
  • crotamitonum
  • crotonyl-N-ethyl-o-toluidine
  • N-ethyl-N-(2-methylphenyl)but-2-enamide
  • N-ethyl-o-crotonotoluidide
Definition
An enamide resulting from the formal condensation of crotonic acid with N-ethyl-2-methylaniline. A colourless or pale yellow oily liquid, it is used in the treatment of pruritus (itching) by producing a counter-irritation: as it evaporates from the skin, it produces a cooling effect that diverts attention away from the itching. It has also been used as an acaricide in the treatment of scabies, though more effective drugs are usually preferred.
References
  • Beilstein:3275497
  • CAS:483-63-6
  • DrugBank:DB00265
  • Drug_Central:744
  • KEGG:D01381
  • LINCS:LSM-3274
  • Patent:GB615137
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from crotamiton
Phenotype where environments contain crotamiton
Phenotype modified by environments containing crotamiton
Human Disease / Model Data
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.