acemetacin

Term ID

CHEBI:31162

Synonyms

• acemetacin
• acemetacina
• acemetacine
• acemetacinum
• Acemix
• Emflex
• indometacin carboxymethyl ester
• indometacin glycolic ester
• indomethacin carboxymethyl ester
• indomethacin glycolic ester
• K 708
• K-708
• Rantudil
• Solart
• TV-1322
• TVX 3322
• {2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetoxy}acetic acid

Definition

A carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used in the treatment of rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation. Its activity is due to both acemetacin and its major metabolite, indometacin.

References

• CAS:53164-05-9
• Drug_Central:47
• KEGG:D01582
• LINCS:LSM-5753
• Patent:DE2234651
• Patent:US3910952
• Reaxys:501672
• Wikipedia:Acemetacin

Ontology

ChEBI  ( EBI )