baclofen

Term ID

CHEBI:2972

Synonyms

• (+-)-Baclofen
• 4-amino-3-(4-chlorophenyl)butanoic acid
• 4-Amino-3-(4-chlorophenyl)butyric acid
• baclofen
• baclofene
• baclofeno
• baclofenum
• beta-(4-Chlorophenyl)gaba
• beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
• beta-(Aminomethyl)-p-chlorohydrocinnamic acid
• beta-(p-Chlorophenyl)-gamma-aminobutyric acid
• DL-4-Amino-3-p-chlorophenylbutanoic acid
• DL-Baclofen
• gamma-Amino-beta-(p-chlorophenyl)butyric acid

Definition

A monocarboxylic acid that is butanoic acid substituted by an amino group at position 4 and a 4-chlorophenyl group at position 3. It acts as a central nervous system depressant, GABA agonist and muscle relaxant.

References

• Beilstein:2104494
• CAS:1134-47-0
• DrugBank:DB00181
• Drug_Central:282
• HMDB:HMDB0014327
• KEGG:D00241
• LINCS:LSM-5169
• PMID:11772961
• PMID:18682277
• PMID:18824012
• Patent:NL6407755
• Patent:US3471548
• Reaxys:2104494
• Wikipedia:Baclofen

Ontology

ChEBI  ( EBI )

Resources

CTD