Search Ontology:
ChEBI
azathioprine
- Term ID
- CHEBI:2948
- Synonyms
-
- 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
- 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
- 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
- Imuran (TN)
- Definition
- A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
- References
-
- CAS:446-86-6
- DrugBank:DB00993
- Drug_Central:269
- KEGG:C06837
- KEGG:D00238
- PMID:11064448
- PMID:15199672
- PMID:15476481
- PMID:15628319
- PMID:15973722
- PMID:16344342
- PMID:16397313
- PMID:16764353
- PMID:16954801
- PMID:17381669
- PMID:17970886
- PMID:18008354
- PMID:18336531
- PMID:19243907
- PMID:20080917
- PMID:25248004
- PMID:25314066
- PMID:25440430
- PMID:25443086
- PMID:25581826
- PMID:25641386
- PMID:28166217
- PMID:8738760
- PMID:9273463
- PMID:9345422
- Reaxys:1225351
- Wikipedia:Azathioprine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
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- has_role
Phenotype
Phenotype resulting from azathioprine
Phenotype where environments contain azathioprine
Phenotype modified by environments containing azathioprine
Human Disease Model