Search Ontology:
ChEBI
busulfan
- Term ID
- CHEBI:28901
- Synonyms
-
- 1,4-Bis(methanesulfonoxy)butane
- 1,4-Butanediol dimethanesulfonate
- 1,4-Dimesyloxybutane
- 1,4-Dimethanesulfonoxybutane
- Bisulfex
- busulfan
- busulfano
- busulfanum
- butane-1,4-diyl dimethanesulfonate
- Leucosulfan
- Mablin
- Mielucin
- Misulban
- Mitostan
- Myeloleukon
- Myleran
- Tetramethylene bis(methanesulfonate)
- Definition
- A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.
- References
-
- CAS:55-98-1
- DrugBank:DB01008
- Drug_Central:438
- KEGG:C06862
- KEGG:D00248
- LINCS:LSM-5388
- PMID:10523796
- PMID:19361744
- PMID:19611402
- Patent:US2917432
- Reaxys:1791786
- Wikipedia:Busulfan
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_functional_parent
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from busulfan
Phenotype where environments contain busulfan
Phenotype modified by environments containing busulfan
Human Disease Model