Search Ontology:
ChEBI
EVP4593
- Term ID
- CHEBI:232358
- Synonyms
-
- 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine
- 6-amino-4-(4-phenoxyphenylethylamino)quinazoline
- 6-amino-4-[2-(4-phenoxyphenyl)ethylamino]quinazoline
- AG-F-89549
- CAY 10470
- CAY-10470
- CAY10470
- EVP 4593
- EVP-4593
- N(4)-(4-phenoxyphenethyl)quinazoline-4,6-diamine
- N(4)-[2-(4-phenoxyphenyl)ethyl]-4,6-quinazolinediamine
- N(4)-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine
- QNZ
- Definition
- A member of the class of quinazolines that is quinazoline substituted by [2-(4-phenoxyphenyl)ethyl]amino and amino groups at positions 4 and 6, respectively. It is an inhibitor of NF-kappaB signal transduction pathway and exhibits protective effects in oncology, cardiovascular disease and parasite invasion.
- References
-
- CAS:545380-34-5
- HMDB:HMDB0246942
- LINCS:LSM-45149
- PMID:21700213
- PMID:28000898
- PMID:28302490
- PMID:28693192
- PMID:30108783
- PMID:30194168
- PMID:30638515
- PMID:30704052
- PMID:31055008
- PMID:32432727
- PMID:34564023
- PMID:34722891
- PMID:35871734
- PMID:36349549
- PMID:36552336
- PMID:36555369
- PMID:36805135
- PMID:37175413
- PMID:37179969
- PMID:37256224
- PMID:38095503
- PMID:39120322
- PMID:39268468
- Reaxys:9350957
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Phenotype
Phenotype resulting from EVP4593
Phenotype where environments contain EVP4593
Phenotype modified by environments containing EVP4593
Human Disease Model