zilucoplan

Term ID

CHEBI:229659

Synonyms

N-{[(2S,5S,8S,11S,14S,22S)-22-acetamido-11-benzyl-8-(3-carbamimidamidopropyl)-5-(2-carboxyethyl)-3,6,9,12,16,23-hexaoxo-2-(propan-2-yl)-1,4,7,10,13,17-hexaazacyclotricosan-14-yl]carbonyl}-N-methyl-L-alpha-aspartyl-3-methyl-L-valyl-L-tyrosyl-3-(1H-pyrrolo[
RA 101495
RA-101495
RA101495
RA3193
zilucoplan
zilucoplanum

Definition

A 15 amino-acid, synthetic macrocyclic peptide with formula C172H278N24O55. Its sodium salt is used for the treatment of generalised myasthenia gravis (a disease that leads to muscle weakness and tiredness) in adults whose immune system produces antibodies against acetylcholine receptors.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: homodetic cyclic peptide macrocycle polyether

homodetic cyclic peptide macrocycle polyether Show first 5 Terms
has_role: complement component 5 inhibitor immunosuppressive agent

complement component 5 inhibitor immunosuppressive agent Show first 5 Terms
inverse is_conjugate_base_of: zilucoplan(4-)

zilucoplan(4-) Show first 5 Terms
is_conjugate_acid_of: zilucoplan(4-)

zilucoplan(4-) Show first 5 Terms

Phenotype

Phenotype resulting from zilucoplan

Phenotype where environments contain zilucoplan

Phenotype modified by environments containing zilucoplan

Human Disease Model