Search Ontology:
ChEBI

trofinetide

Term ID
CHEBI:229599
Synonyms
  • (2S)-2-({[(2S)-1-(aminoacetyl)-2-methylpyrrolidin-2-yl]carbonyl}amino)pentanedioic acid
  • (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl]amino}pentanedioic acid
  • Daybue
  • glycyl-2-methyl-L-prolyl-L-glutamic acid
  • NNZ 2566
  • NNZ-2566
  • NNZ2566
  • trofinetida
  • trofinetide
  • trofinetidum
Definition
A tripeptide comprising of glycine, 2-methyl-L-proline, and L-glutamic acid joined in sequence by peptide linkages. It is the first and only treatment approved by the FDA specifically indicated for Rett syndrome in adults and pediatric patients two years of age and older.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from trofinetide
Phenotype where environments contain trofinetide
Phenotype modified by environments containing trofinetide
Human Disease Model
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