Search Ontology:
ChEBI

etrasimod

Term ID
CHEBI:229230
Synonyms
  • (R)-2-(7-((4-cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
  • [(3R)-7-{[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy}-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]acetic acid
  • APD 334
  • APD-334
  • APD334
  • etrasimod
  • etrasimodum
Definition
An organic heterotricyclic compound that is 1,2,3,4-tetrahydrocyclopenta[b]indole substituted by carboxymethyl and [4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy groups at positions 3R and 7, respectively. It is a potent and functional antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50 = 1.88 nM in CHO cells).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse is_conjugate_base_of
is_conjugate_acid_of
Phenotype
Phenotype resulting from etrasimod
Phenotype where environments contain etrasimod
Phenotype modified by environments containing etrasimod
Human Disease Model
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