Search Ontology:
ChEBI
unfolded protein
- Term ID
- CHEBI:194424
- Synonyms
-
- disordered protein
- disordered proteins
- intrinsically disordered protein
- intrinsically disordered proteins
- intrinsically unstructured protein
- intrinsically unstructured proteins
- misfolded protein
- misfolded proteins
- natively unfolded protein
- natively unfolded proteins
- unfolded proteins
- unstructured protein
- unstructured proteins
- Definition
- A protein that lacks a well defined tertiary structure. These proteins are flexible, non-compact (extended) and have little or no ordered secondary structure under physiological conditions. They are involved in several cellular processes (E.g. signalling, targeting and DNA binding) and may play important roles in the development of cancer and amyloidotic diseases.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
-
Show first 5 Terms
Phenotype
Phenotype resulting from unfolded protein
Phenotype where environments contain unfolded protein
Phenotype modified by environments containing unfolded protein
Human Disease Model