Search Ontology:
ChEBI
7-methyl-guanosine-5'-triphosphate-5'-guanosine
- Term ID
- CHEBI:191209
- Synonyms
-
- 2-amino-9-[(2R,3R,4S,5R)-5-({[{[{[{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-me
- 7-methyl-diguanosine triphosphate
- 7-methyl-GpppG
- [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-7-ium-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl] hydrogen phosphate
- m(7)G(5')ppp(5')G
- m(7)GP3G
- m(7)GP3G (monomethylated cap analog)
- m(7)GpppG
- mRNA cap analog N(7)-methyl GpppG
- N(7)-MeGpppG
- P(1)-(5'-7-methyl-guanosyl) P(3)-(5'-(guanosyl))triphosphate
- Definition
- A guanosine 5'-phosphate that is 7-methyl-GTP in which the hydroxy group of the terminal phosphate is substituted by a guanosinyl group. It is a cap analog that can be incorporated into mRNA.
- References
-
- CAS:62828-64-2
- Chemspider:108799
- DrugBank:DB03958
- PDBeChem:GTG
- PMID:10981813
- PMID:11156290
- PMID:12374755
- PMID:12454499
- PMID:12464184
- PMID:14731396
- PMID:15068804
- PMID:16767703
- PMID:17363367
- PMID:18066781
- PMID:18614538
- PMID:19217398
- PMID:19269171
- PMID:19710013
- PMID:22316555
- PMID:22985415
- PMID:25150228
- PMID:25228490
- PMID:25834778
- PMID:26294658
- PMID:26559973
- PMID:26779415
- PMID:27236792
- PMID:32950529
- Patent:WO2017066781
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_functional_parent
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- inverse is_conjugate_base_of
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- is_conjugate_acid_of
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Phenotype
Phenotype resulting from 7-methyl-guanosine-5'-triphosphate-5'-guanosine
Phenotype where environments contain 7-methyl-guanosine-5'-triphosphate-5'-guanosine
Phenotype modified by environments containing 7-methyl-guanosine-5'-triphosphate-5'-guanosine
Human Disease Model