Search Ontology:
ChEBI
PB28
- Term ID
- CHEBI:189648
- Synonyms
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- 1-(3-(5-methoxytetralin-1-yl)propyl)-4-cyclohexylpiperazine
- 1-cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine
- 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl]piperazine
- 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine
- PB 28
- PB-28
- Definition
- A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.
- References
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- CAS:172906-90-0
- Chemspider:8649746
- PMID:15322732
- PMID:16687172
- PMID:16891467
- PMID:18178434
- PMID:19200007
- PMID:19842660
- PMID:20021355
- PMID:20077462
- PMID:21229979
- PMID:21684636
- PMID:21744858
- PMID:22890883
- PMID:23399765
- PMID:24697311
- PMID:25637276
- PMID:28086830
- PMID:28764962
- PMID:29438891
- PMID:31994091
- PMID:33052254
- PMID:33364961
- PMID:34783163
- Wikipedia:PB-28
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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Phenotype
Phenotype resulting from PB28
Phenotype where environments contain PB28
Phenotype modified by environments containing PB28
Human Disease Model