12-ketomethymycin

Term ID

CHEBI:188461

Synonyms

(3R,4S,5S,7R,9E,11R,12R)-12-acetonyl-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside

Definition

A macrolide that is 10-deoxymethymycin with the ethyl group at position 12 replaced with an acetonyl group. It is a natural product synthesized by Streptomyces sp. AM4900 with weak cytotoxicity against SKOV-3 and Jurkat cells.

References

PMID:33590846

Ontology

ChEBI ( EBI )

Relationships

is a type of: enone macrolide monosaccharide derivative

enone macrolide monosaccharide derivative Show first 5 Terms
has_functional_parent: 10-deoxymethymycin

10-deoxymethymycin Show first 5 Terms
has_role: antineoplastic agent bacterial metabolite

antineoplastic agent bacterial metabolite Show first 5 Terms
inverse has_functional_parent: 12-ketomethymycin N-oxide

12-ketomethymycin N-oxide Show first 5 Terms

Phenotype

Phenotype resulting from 12-ketomethymycin

Phenotype where environments contain 12-ketomethymycin

Phenotype modified by environments containing 12-ketomethymycin

Human Disease Model