Search Ontology:
ChEBI

AR-42

Term ID
CHEBI:188197
Synonyms
  • (S)-HDAC 42
  • (S)-HDAC-42
  • AR 42
  • AR42
  • HDAC-42
  • N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide
  • N-hydroxy-4-{[(2S)-3-methyl-2-phenylbutanoyl]amino}benzamide
  • OSU-HDAC42
  • REC 2282
  • REC-2282
  • REC2282
Definition
A secondary carboxamide resulting from the formal condensation of the carboxy group of (2S)-3-methyl-2-phenylbutanoic acid with the amino group of 4-amino-N-hydroxybenzamide. It is a pan-HDAC inhibitor that was in clinical development for the treatment of hematological malignancies and solid tumours.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from AR-42
Phenotype where environments contain AR-42
Phenotype modified by environments containing AR-42
Human Disease Model
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