alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group

Term ID

CHEBI:17785

Synonyms

alpha-D-Gal(1->3)-beta-D-Gal(1->4)-D-GlcNAc-yl group
alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-GlcNHAc-R
alpha-D-galactopyranosyl-(1->3) beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-D-glucopyranosyl
alpha-D-galactopyranosyl-(1->3) beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-D-glucopyranosyl group
alpha-D-galactopyranosyl-(1->3)-beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-D-glucopyranosyl
alpha-D-Galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R
alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl group
alpha-D-Galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R
alpha-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl group
alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp-NAc-yl group
alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNHAc-R
alpha-gal
alpha-Gal trisaccharide
alpha-Gal trisaccharide epitope
alpha-Gal3
alpha-galactosyl epitope
Gal(alpha1->3)-Gal(beta1->4)-GlcNAc-R
Galalpha1-3Galbeta1-4GlcNAc-
Galalpha1-3LacNAc-

Definition

An N-acetyl-D-glucosaminyl group comprising one N-acetylated glucosamine and two galactose residues, linked as shown. A trisaccharide antigen found in all animals apart from Old World primates and humans, it is the main xenoantigen hampering the success of clinical xenotransplantation. Obtained formally by removing the hydroxy group from the hemiacetal function of the amino trisaccharide alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: N-acetyl-D-glucosaminyl groups

N-acetyl-D-glucosaminyl groups Show first 5 Terms
has subtype: alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc-yl group

alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc-yl group Show first 5 Terms
has_role: carbohydrate allergen epitope xenoantigen

carbohydrate allergen epitope xenoantigen Show first 5 Terms
inverse has_part: biotinylated alpha-gal

biotinylated alpha-gal Show first 5 Terms
is_substituent_group_from: alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc

alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc Show first 5 Terms

Phenotype

Phenotype resulting from alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group

Phenotype where environments contain alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group

Phenotype modified by environments containing alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group

Human Disease Model