Search Ontology:
ChEBI
2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
- Term ID
- CHEBI:177299
- Synonyms
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- (R)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
- 2-[4-(3R)-3-piperidinylphenyl]-2H-indazole-7-carboxamide
- 2-[4-[(3R)-piperidin-3-yl]phenyl]indazole-7-carboxamide
- 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
- ent-niraparib
- MK-4827 (R-enantiomer)
- niraparib (R-enantiomer)
- Definition
- A 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM.
- References
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- CAS:1038915-58-0
- Chemspider:24671122
- PMID:25761096
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
Phenotype where environments contain 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
Phenotype modified by environments containing 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
Human Disease / Model Data