Search Ontology:
ChEBI

ferrostatin-1

Term ID
CHEBI:173086
Synonyms
  • 3-amino-4-cyclohexylaminobenzoic acid ethyl ester
  • ethyl 3-amino-4-(cyclohexylamino)benzoate
  • Fer-1
  • ferrrostatin 1
Definition
An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from ferrostatin-1
Phenotype where environments contain ferrostatin-1
Phenotype modified by environments containing ferrostatin-1
Human Disease Model
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.