Search Ontology:
ChEBI

ferrostatin-1

Term ID
CHEBI:173086
Synonyms
  • 3-amino-4-cyclohexylaminobenzoic acid ethyl ester
  • ethyl 3-amino-4-(cyclohexylamino)benzoate
  • Fer-1
  • ferrrostatin 1
Definition
An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from ferrostatin-1
Phenotype where environments contain ferrostatin-1
Phenotype modified by environments containing ferrostatin-1
Human Disease / Model Data
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