progesterone

Term ID

CHEBI:17026

Synonyms

(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
17alpha-progesterone
4-Pregnene-3,20-dione
Agolutin
Akrolutin
corpus luteum hormone
Crinone
Delta(4)-pregnene-3,20-dione
Gelbkoerperhormon
luteohormone
pregn-4-ene-3,20-dione
Progesteron
Progesterone

Definition

A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.

References

CAS:57-83-0
DrugBank:DB00396
Drug_Central:2279
Gmelin:708590
HMDB:HMDB0001830
KEGG:C00410
KEGG:D00066
MetaCyc:PROGESTERONE
PDBeChem:STR
PMID:10438974
PMID:9506942
Reaxys:1915950
Wikipedia:Progesterone

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 3-oxo-Delta(4) steroid 20-oxo steroid C21-steroid hormone

3-oxo-Delta(4) steroid 20-oxo steroid C21-steroid hormone Show first 5 Terms
has_parent_hydride: pregnane

pregnane Show first 5 Terms
has_role: contraceptive drug human metabolite mouse metabolite progesterone receptor agonist progestin

contraceptive drug human metabolite mouse metabolite progesterone receptor agonist progestin Show first 5 Terms
inverse has_functional_parent: 2,5-dioxo-1-pyrrolidinyl 6-(6-{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl}amino)hexanoate 3-(progesterone-4-yl)thiopropionic acid 3-(progesterone-7alpha-yl)thiopropionic acid 4-pregnen-3beta,20alpha-diol 4-pregnen-3beta-ol-20-one ... Show All 24 Terms

2,5-dioxo-1-pyrrolidinyl 6-(6-{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl}amino)hexanoate 3-(progesterone-4-yl)thiopropionic acid 3-(progesterone-7alpha-yl)thiopropionic acid 4-pregnen-3beta,20alpha-diol 4-pregnen-3beta-ol-20-one 5alpha-pregnane-3,20-dione 6-(6-{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl}amino)hexanoic acid 6-{3-[(progesterone-4-yl)thiopropionyl]amino}hexanoic acid 6beta,16alpha,17alpha-trihydroxyprogesterone 9-fluoro-2alpha-methylpregn-4-ene-3,11,20-trione 11,21-dioxoprogesterone 11-deoxycorticosterone 11alpha-hydroxyprogesterone 11beta-hydroxyprogesterone 12alpha-hydroxyprogesterone 15beta-hydroxyprogesterone 16,17-didehydroprogesterone 16alpha-hydroxyprogesterone 16beta-methylpregn-4-ene-3,20-dione 17alpha-hydroxyprogesterone 21-dehydrocortisol 21-dehydrocortisone Delta(1)-progesterone progesterone 3-O-(carboxymethyl)oxime Show first 5 Terms

Phenotype

Phenotype resulting from progesterone

Phenotype where environments contain progesterone

Phenotype modified by environments containing progesterone

Human Disease Model